{"id":360,"date":"2022-08-06T09:35:19","date_gmt":"2022-08-06T09:35:19","guid":{"rendered":"https:\/\/www.snijderlab.org\/news\/?p=360"},"modified":"2022-08-06T11:20:12","modified_gmt":"2022-08-06T11:20:12","slug":"immune-wiring-pharmacoscopy-nature","status":"publish","type":"post","link":"https:\/\/www.snijderlab.org\/news\/2022\/08\/06\/immune-wiring-pharmacoscopy-nature\/","title":{"rendered":"Immune wiring + pharmacoscopy @ Nature"},"content":{"rendered":"\n<p>The Snijder lab contributed to a wonderful study published in Nature, led by Jarrod Shilts and Gavin Wright from the Wellcome Sanger Institute, and in collaboration with others: <\/p>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\"><p><a rel=\"noreferrer noopener\" href=\"https:\/\/www.nature.com\/articles\/s41586-022-05028-x\" target=\"_blank\"><\/a><a rel=\"noreferrer noopener\" href=\"https:\/\/www.nature.com\/articles\/s41586-022-05028-x\" target=\"_blank\">A physical wiring diagram for the human immune system | Nature<\/a><\/p><\/blockquote>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:100%\">\n<p>The study combines careful protein-protein interaction analysis of proteins expressed on the surface of immune cells with pharmacoscopy-based measurement of how those proteins perturb cell-cell contacts among immune cells. On our side, this work was performed by <a rel=\"noreferrer noopener\" href=\"https:\/\/www.linkedin.com\/in\/yannik-severin-328880241\/\" data-type=\"URL\" data-id=\"https:\/\/www.linkedin.com\/in\/yannik-severin-328880241\/\" target=\"_blank\">Yannik Severin<\/a>, using his beautiful single-round multiplexed immunofluorescence protocol to perform image-based screening of human immune cells <a rel=\"noreferrer noopener\" href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/2021.12.03.471105v1\" data-type=\"URL\" data-id=\"https:\/\/www.biorxiv.org\/content\/10.1101\/2021.12.03.471105v1\" target=\"_blank\">detailed on bioarxiv<\/a>.<\/p>\n<\/div>\n<\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large\"><img decoding=\"async\" src=\"https:\/\/ethz.ch\/en\/news-and-events\/eth-news\/news\/2022\/08\/first-map-of-immune-system-connections-reveals-new-therapeutic-opportunities\/_jcr_content\/articleLeadImage\/image.imageformat.carousel.2052810547.jpg\" alt=\"\"\/><figcaption>Single-round multiplexed immunofluorescence of human immune cells by Yannik Severin et al.<\/figcaption><\/figure>\n<\/div>\n\n\n<p>Also be sure to check out the great write-up by the <a rel=\"noreferrer noopener\" href=\"https:\/\/ethz.ch\/en\/news-and-events\/eth-news\/news\/2022\/08\/first-map-of-immune-system-connections-reveals-new-therapeutic-opportunities.html\" data-type=\"URL\" data-id=\"https:\/\/ethz.ch\/en\/news-and-events\/eth-news\/news\/2022\/08\/first-map-of-immune-system-connections-reveals-new-therapeutic-opportunities.html\" target=\"_blank\">ETH Zurich News<\/a> team and wonderful Twitter posts by <a rel=\"noreferrer noopener\" href=\"https:\/\/twitter.com\/JarrodShilts\/status\/1554857851499253760\" data-type=\"URL\" data-id=\"https:\/\/twitter.com\/JarrodShilts\/status\/1554857851499253760\" target=\"_blank\">Jarrod Shilts<\/a> and <a rel=\"noreferrer noopener\" href=\"https:\/\/twitter.com\/EricTopol\/status\/1554868139665473536\" data-type=\"URL\" data-id=\"https:\/\/twitter.com\/EricTopol\/status\/1554868139665473536\" target=\"_blank\">Eric Topol<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The Snijder lab contributed to a wonderful study published in Nature, led by Jarrod Shilts and Gavin Wright from the Wellcome Sanger Institute, and in collaboration with others: A physical wiring diagram for the human immune system | Nature The study combines careful protein-protein interaction analysis of proteins expressed on the surface of immune cells&hellip; <a class=\"more-link\" href=\"https:\/\/www.snijderlab.org\/news\/2022\/08\/06\/immune-wiring-pharmacoscopy-nature\/\">Continue reading <span class=\"screen-reader-text\">Immune wiring + pharmacoscopy @ Nature<\/span> <span class=\"meta-nav\" aria-hidden=\"true\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1,5],"tags":[],"class_list":["post-360","post","type-post","status-publish","format-standard","hentry","category-news","category-publications"],"_links":{"self":[{"href":"https:\/\/www.snijderlab.org\/news\/wp-json\/wp\/v2\/posts\/360","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.snijderlab.org\/news\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.snijderlab.org\/news\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.snijderlab.org\/news\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.snijderlab.org\/news\/wp-json\/wp\/v2\/comments?post=360"}],"version-history":[{"count":9,"href":"https:\/\/www.snijderlab.org\/news\/wp-json\/wp\/v2\/posts\/360\/revisions"}],"predecessor-version":[{"id":380,"href":"https:\/\/www.snijderlab.org\/news\/wp-json\/wp\/v2\/posts\/360\/revisions\/380"}],"wp:attachment":[{"href":"https:\/\/www.snijderlab.org\/news\/wp-json\/wp\/v2\/media?parent=360"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.snijderlab.org\/news\/wp-json\/wp\/v2\/categories?post=360"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.snijderlab.org\/news\/wp-json\/wp\/v2\/tags?post=360"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}