{"id":386,"date":"2022-11-05T19:41:00","date_gmt":"2022-11-05T19:41:00","guid":{"rendered":"https:\/\/www.snijderlab.org\/news\/?p=386"},"modified":"2024-09-26T13:06:36","modified_gmt":"2024-09-26T13:06:36","slug":"phenoplexing-sciadv","status":"publish","type":"post","link":"https:\/\/www.snijderlab.org\/news\/2022\/11\/05\/phenoplexing-sciadv\/","title":{"rendered":"Phenoplexing @ SciAdv"},"content":{"rendered":"<div class=\"wp-block-image\">\n<figure class=\"alignleft size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/biol.ethz.ch\/en\/news-and-events\/d-biol-news\/2022\/11\/immune-cells-a-picture-worth-a-thousand-words\/_jcr_content\/wide_content\/textimage\/image.imageformat.text50percent.1744959915.jpg\" alt=\"\" width=\"238\" height=\"243\"\/><\/figure>\n<\/div>\n\n\n<p>Yannik&#8217;s paper on our single-round multiplexed immunofluorescence assay for the high throughput screening of human immune cells is <a rel=\"noreferrer noopener\" href=\"https:\/\/www.science.org\/doi\/10.1126\/sciadv.abn5631\" data-type=\"URL\" data-id=\"https:\/\/www.science.org\/doi\/10.1126\/sciadv.abn5631\" target=\"_blank\">out in Science Advances<\/a>! We (sometimes) call the approach <strong>Phenoplexing<\/strong>.<\/p>\n\n\n\n<p>The observations stemming from the approach are remarkable: immune cell morphologies reveal an amazing amount of information on the health status of the blood donor, including age, sex, blood pressure, and inflammation. <\/p>\n\n\n\n<p>The approach was first used in Jarrod Shilts&#8217; <a href=\"https:\/\/www.nature.com\/articles\/s41586-022-05028-x\" data-type=\"URL\" data-id=\"https:\/\/www.nature.com\/articles\/s41586-022-05028-x\" target=\"_blank\" rel=\"noreferrer noopener\">Nature paper<\/a> on immune cell wiring diagram.<\/p>\n\n\n\n<p>Please also see this cool write-up at the <a rel=\"noreferrer noopener\" href=\"https:\/\/biol.ethz.ch\/en\/news-and-events\/d-biol-news\/2022\/11\/immune-cells-a-picture-worth-a-thousand-words.html\" data-type=\"URL\" data-id=\"https:\/\/biol.ethz.ch\/en\/news-and-events\/d-biol-news\/2022\/11\/immune-cells-a-picture-worth-a-thousand-words.html\" target=\"_blank\">ETH D-BIOL news<\/a> &amp; another <a rel=\"noreferrer noopener\" href=\"https:\/\/twitter.com\/EricTopol\/status\/1587892901970706432\" data-type=\"URL\" data-id=\"https:\/\/twitter.com\/EricTopol\/status\/1587892901970706432\" target=\"_blank\">retweet by Eric Topol<\/a> :-). <\/p>\n","protected":false},"excerpt":{"rendered":"<p>Yannik&#8217;s paper on our single-round multiplexed immunofluorescence assay for the high throughput screening of human immune cells is out in Science Advances! We (sometimes) call the approach Phenoplexing. The observations stemming from the approach are remarkable: immune cell morphologies reveal an amazing amount of information on the health status of the blood donor, including age,&hellip; <a class=\"more-link\" href=\"https:\/\/www.snijderlab.org\/news\/2022\/11\/05\/phenoplexing-sciadv\/\">Continue reading <span class=\"screen-reader-text\">Phenoplexing @ SciAdv<\/span> <span class=\"meta-nav\" aria-hidden=\"true\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1,5],"tags":[],"class_list":["post-386","post","type-post","status-publish","format-standard","hentry","category-news","category-publications"],"_links":{"self":[{"href":"https:\/\/www.snijderlab.org\/news\/wp-json\/wp\/v2\/posts\/386","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.snijderlab.org\/news\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.snijderlab.org\/news\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.snijderlab.org\/news\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.snijderlab.org\/news\/wp-json\/wp\/v2\/comments?post=386"}],"version-history":[{"count":1,"href":"https:\/\/www.snijderlab.org\/news\/wp-json\/wp\/v2\/posts\/386\/revisions"}],"predecessor-version":[{"id":387,"href":"https:\/\/www.snijderlab.org\/news\/wp-json\/wp\/v2\/posts\/386\/revisions\/387"}],"wp:attachment":[{"href":"https:\/\/www.snijderlab.org\/news\/wp-json\/wp\/v2\/media?parent=386"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.snijderlab.org\/news\/wp-json\/wp\/v2\/categories?post=386"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.snijderlab.org\/news\/wp-json\/wp\/v2\/tags?post=386"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}